(2024)
Toxic effects of triclosan in aquatic organisms: A review focusing on single and combined exposure of environmental conditions and pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT.
920,
170902
(2024)
Single and combined effects of increased temperature and methylmercury on different stages of the marine rotifer Brachionus plicatilis.
JOURNAL OF HAZARDOUS MATERIALS.
466,
133448
(2024)
Combined effects of nanoplastics and elevated temperature in the freshwater water flea Daphnia magna.
JOURNAL OF HAZARDOUS MATERIALS.
465,
133325
(2023)
Sulfur-Directed α-C(sp3)-H Amidation of Pyrrolidines with Dioxazolones under Rhodium Catalysis.
ORGANIC LETTERS.
xx,
xx
(2023)
An integrated in vitro approach to identifying chemically induced oxidative stress and toxicity in mitochondria.
CHEMOSPHERE.
349,
140857
(2023)
Dendropanoxide attenuates high glucose-induced oxidative damage in NRK52E cells via AKT/mTOR signaling pathway.
PLANTA MEDICA.
xx,
xx
(2023)
Chlorophyll a and novel synthetic derivatives alleviate atopic dermatitis by suppressing Th2 cell differentiation via IL-4 receptor modulation.
CLINICAL IMMUNOLOGY.
258,
109852
(2023)
Sesamin ameliorates lipotoxicity and lipid accumulation through the activation of the estrogen receptor alpha signaling pathway.
BIOCHEMICAL PHARMACOLOGY.
216,
115768
(2023)
Cationic nanoplastic causes mitochondrial dysfunction in neural progenitor cells and impairs hippocampal neurogenesis.
FREE RADICAL BIOLOGY AND MEDICINE.
208,
2023
(2023)
MHY446 Induces Apoptosis via Reactive Oxygen Species-mediated Endoplasmic Reticulum Stress in HCT116 Human Colorectal Cancer Cells.
JOURNAL OF CHEMOTHERAPY.
xxx,
xxx
(2023)
Physiological effects and molecular response in the marine rotifer<i> Brachionus</i><i> plicatilis</i> after combined exposure to nanoplastics and copper.
MARINE POLLUTION BULLETIN.
194,
(2023)
Synergistic toxic mechanisms of microplastics and triclosan via multixenobiotic resistance (MXR) inhibition-mediated autophagy in the freshwater water flea Daphnia magna.
SCIENCE OF THE TOTAL ENVIRONMENT.
896,
165214
(2023)
Dendropanoxide Alleviates Thioacetamide-induced Hepatic Fibrosis via Inhibition of ROS Production and Inflammation in BALB/C Mice.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES.
19,
9
(2023)
Anti-inflammatory effect and metabolic mechanism of BS012, a mixture of Asarum sieboldii, Platycodon grandiflorum, and Cinnamomum cassia extracts, on atopic dermatitis in vivo and in vitro.
PHYTOMEDICINE.
115,
154818
(2023)
Synthesis and biological evaluation of atropisomeric tetrahydroisoquinolines overcoming docetaxel resistance in triple-negative human breast cancer cells.
BIOORGANIC CHEMISTRY.
137,
(2023)
Low-dose curcumin enhances hippocampal neurogenesis and memory retention in young mice.
ARCHIVES OF PHARMACAL RESEARCH.
46,
5
(2023)
Apocynin abrogates methotrexate‑induced nephrotoxicity: role of TLR4/NF‑κB‑p65/p38‑MAPK, IL‑6/STAT‑3, PPAR‑γ, and SIRT1/FOXO3 signaling pathways.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY.
46,
4
(2023)
Metallothionein 3 Inhibits 3T3-L1 Adipocyte Differentiation via Reduction of Reactive Oxygen Species.
ANTIOXIDANTS.
12,
3
(2023)
Physiologically Based Pharmacokinetic Modelling to Predict Pharmacokinetics of Enavogliflozin, a Sodium-Dependent Glucose Transporter 2 Inhibitor, in Humans.
PHARMACEUTICS.
2022,
14
(2023)
Fibrinogen on extracellular vesicles derived from polyhexamethylene guanidine phosphate-exposed mice induces inflammatory effects via integrin β.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.
252,
-
Publications
(2021)
Evidence Based Validation of Traditional Medicines- A Comprehensive Approach; Bioactive Natural Leads Targeting Cancer Cell Metabolism.
Springer.
Lead author
(2019)
Antioxidants and Toxicology :Chapter 52 Curcumin, cadmium toxicity and oxidative stress.
Elsevier.
Lead author
(2019)
An Introduction to Interdisciplinary Toxicology: From Molecules to Man.
Elsevior.
Solo
(2018)
Polysaccharide-based Nano-Biocarrier in Drug Delivery
-Chapter 5: Heparin and its Derivatives-Based Nanoparticles for Cancer Therapy.
CRC Press.
Lead author
(2017)
항암 타깃을 위한 Autophagy inducers의 응용 및 기전규명.
한국응용약물학회.
Solo
(2017)
Lu's Basic Toxicology.
Taylor & Francis.
Solo
(2017)
예방약학 제 8판.
신일북스.
Co-author
Patent/Intellectual Property
신규한 인돌 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 비만 예방 또는 치료용 약학적 조성물.
10-2021-0000812.
20210827.
KOREA, REPUBLIC OF
신장질환 조기 진단용 바이오마커 pyruvate kinase M2 (PKM2) 및 이의 이용.
10-2018-0065640.
20200625.
KOREA, REPUBLIC OF
골손실의 완화, 치료 또는 예방용 약학조성물 및 건강기능식품.
10-2018-0007317.
20200529.
KOREA, REPUBLIC OF
펜치논 에이 및 그 유도체의 제조방법과 이를 유효성분으로 포함하는 항염증 조성물.
10-2017-0131446.
20191127.
KOREA, REPUBLIC OF
1-아미노인단 및 이의 제조방법.
10-2018-0001194.
20191011.
KOREA, REPUBLIC OF
피롤로인돌리디온 유도체, 및 이의 제조방법.
10-2017-0049254.
20191010.
KOREA, REPUBLIC OF
이리듐 촉매를 이용한 아미노벤즈알데히드의 제조방법, 이를 이용한 화합물 및 이를 유효성분으로 포함하는 염증성 질환의 예방 또는 치료용 약학적 조성물.
10-2017-0096491.
20190712.
KOREA, REPUBLIC OF
Oxindoles derivatives, preparation method thereof and pharmaceutical compositions for the prevention or treatment of cancer containing the same as an active ingredient.
US 20180339964 A1__-____-_______.
20190618.
UNITED STATES
인돌 유도체를 유효성분으로 포함하는 당뇨병 예방 또는 치료용 약학적 조성물.
10-2019-0009010.
20190425.
KOREA, REPUBLIC OF
신규 스파이로아이소인돌리논 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암예방 및 치료용 조성물.
10-2016-0169438.
20190422.
KOREA, REPUBLIC OF
아조벤젠과 이중결합을 이용한 2,3-이중치환 인돌 유도체의 제조방법, 이를 이용한 화합물, 및 이를 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물.
10-2017-0097610.
20190418.
KOREA, REPUBLIC OF
옥시인돌 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암 예방 또는 치료용 조성물.
10-2017-0065385.
20190306.
KOREA, REPUBLIC OF
신규 인돌 유도체, 이의 제조방법, 및 이를 유효성분으로 포함하는 당뇨병 예방 또는 치료용 약학적 조성물.
10-2018-0136227.
20190228.
KOREA, REPUBLIC OF
개똥쑥 추출물의 분획물과 특정 소분획을 유효성분으로 함유하는 신장암 예방 및 치료용약학조성물.
10-2017-0076630.
20190215.
KOREA, REPUBLIC OF
로듐 촉매를 이용한 아미드화 인돌린의 제조방법, 이를 이용한 화합물 및 이를 유효성분으로 포함하는 암예방 및 치료용 약학적 조성물.
10-2016-0123108.
20181010.
KOREA, REPUBLIC OF
N-아로일우레아 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암 예방 및 치료용 조성물.
10-2017-0049253.
20180411.
KOREA, REPUBLIC OF
아로일우레아 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암 예방 및 치료용 조
성물.
10-2017-0049253.
20180411.
KOREA, REPUBLIC OF
신장질환 조기 진단용 바이오마커 SBP1 및 이의 이용.
PCT/KR2017/008911.
20170921.
KOREA, REPUBLIC OF
신장독성 평가용 바이오마커 AKR7A1 및 이를 이용한 신장독성 평가 방법.
특허-2013-0119820.
20151204.
KOREA, REPUBLIC OF
Conference Paper
(2023)
A new synthetic peptide DS-2 enhanced anti-tumor activity by targeting human telomerase reverse transcriptase (hTERT) in prostate cancer cells.
AACR.
UNITED STATES
(2022)
Potential toxicity of polystyrene microplastics with different particle size and surface charge in human lung epithelial BEAS-2B cells and HaCaT keratinocytes.
APR.
KOREA, REPUBLIC OF
(2022)
A novel synthetic peptide DS-2 targets human telomerase reverse transcriptase (hTERT) in prostate cancer cells.
48th annual meeting Korean Cancer Association.
KOREA, REPUBLIC OF
(2022)
Effects of triclosan on in vivo endpoints, antioxidant defense, and DNA damage response in the water flea Daphnia magna over multiple generation.
EUROTOX2022.
NETHERLANDS
(2022)
Tenovin-1 attenuates hepatic inflammation and fibrosis in high fat diet-induced non-alcoholic steatohepatitis.
EUROTOX2022.
NETHERLANDS
(2022)
Dendropanoxide alleviates thioacetamide-induced hepatic fibrosis by attenuation of oxidative stress and apoptosis via TGF-beta/Smad signaling pathway.
EUROTOX2022.
NETHERLANDS
(2022)
Potential toxicity of polystyrene microplastics with different particle size and surface charge in human lung epithelial BEAS-2B cells.
Eurotox.
NETHERLANDS
(2022)
A specific pyruvate kinase M2 inhibitor, compound 3K, induces autophagy-dependent cell death via the regulation of glycolysis in human ovarian cancer cells.
대한약학회.
KOREA, REPUBLIC OF
(2021)
A new synthetic peptide DS-2 targets human telomerase reverse transcriptase (hTERT) in human prostate cancer cells.
대한약학회.
KOREA, REPUBLIC OF
(2021)
Compound 3K, a specific pyruvate kinase M2 inhibitor, induces autophagy-dependent ovarian cancer cell death via regulation of glycolysis.
분자세포생물학회.
KOREA, REPUBLIC OF
(2021)
Prospective roles og Glioma-associated oncogene homolog 1 in glucose metabolism of human triple-negative breast cancer cells.
한국독성학회/발암원학회.
KOREA, REPUBLIC OF
(2021)
Dendropanoxide protect against thioacetamide-induced liver fibrosis by attenuating TGF-b1/SMADS pathways in Balb/c mice.
한국독성학회/발암원학회.
KOREA, REPUBLIC OF
(2021)
Protective effect of Macaranga Denticulata on renal fibrosis in streptozocin-induced diabetic nephropathy.
한국독성학회/발암원학회.
KOREA, REPUBLIC OF
(2021)
Protective effect of SIRT-2 inhibitor, Tenovin-1, against high fat diet-induced nephropathy.
한국독성학회/발암원학회.
KOREA, REPUBLIC OF
(2021)
A low dose of aripiprazole has the strongest sensitization effect among 19 respositioned bipolar drugs in P-gp-overexpressing drug-resistant cancer cells.
대한약학회.
KOREA, REPUBLIC OF
(2020)
Identification of novel biomarkers for early predicting diabetic nephropathy.
한국독성학회 추계학술대회.
KOREA, REPUBLIC OF
(2020)
Protective effect of EX527 against HFD-induced DN via ameliorating oxidative stress and inflammation.
한국독성학회 추계학술대회.
KOREA, REPUBLIC OF
(2020)
Compound 3K, a specific pyruvate kinase M2 inhibitor, induces autophagic cell death through the disruption of the glycolytic pathway in ovarian cancer cells.
대한약학회 추계학술대회.
KOREA, REPUBLIC OF
(2020)
Identification of novel biomarkers for early detection of diabetic nephropathy.
대한약학회 추계학술대회.
KOREA, REPUBLIC OF
(2019)
Protective effect of SIRT-1 inhibitor, EX527, against high fat diet-induced nephrotoxicity.
Toxicology Letters.
FINLAND
